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Developing functional foods to combat major causes of death
   

Ventures Process

Principal holdings
    Novocellus
    Geomerics
    Parsortix

Other holdings
    Aguru Images
    NeuroTargets
    Acolyte Biomedica
    Synature

Exits
    Provexis
    Exago

Provexis plc (Proprietary nutraceuticals)

> Visit company website

Proven novel ingredients for functional foods

Overview
Provexis was established by ANGLE in 2000 to develop and license a range of scientifically-tested products based on natural, bioactive ingredients. The first product is a heart health product.  Provexis listed on AIM in June 2005 through a reverse takeover of Nutrinnovator Holdings plc.

Background

Almost half of all deaths in Europe are a result of circulatory disease, including heart attack and stroke.  As the finger of blame for the rise in such conditions points to poor diet, a market is looking for natural solutions that counteract this trend.

In response, Provexis developed Fruitflow®, a patented bioactive extract of tomato that inhibits platelet aggregation.  Within just three hours of consumption a noticeable effect is observable, reducing the risk of thrombosis which underpins heart attack and stroke.  This gives Fruitflow® elite status as one of only a few products available to carry a scientifically substantiated health claim: ‘Helps maintain a healthy heart and benefit circulation.’

In an increasingly health-conscious society looking for products which are both effective and natural in origin, Provexis aims to develop further novel, patented active food components for integration into innovative functional foods and beverages. These development programmes are typically undertaken in partnership with leading academic research establishments and always aim to develop products that have a health benefit which is both clearly defined and scientifically proven.

Market opportunity
A Mintel report published in August 2005 estimated the market for heart healthy products was worth $18bn per annum in the US alone. This market is forecast to grow by 16% by 2010.

In addition, a number of further products are in the pipeline.  These include a plantain extract which will underpin a novel medical food for the dietary management of Inflammatory Bowel Disease.

Progress
Provexis listed share price has proved volatile while it seeks to conclude major corporate deals for its products. However its market capitalisation has exceeded £100 million in August and September 2009.

Website: www.provexis.com